Tetrapyrroles and derivatives
Chemscene ChemScene | (S)-3-hydroxydihydrofuran-2(3H)-one | 250MG | CS-0312594 | 0.97 | 52079-23-9| MFCD00211245 | 102.09
ChemScene | (S)-3-hydroxydihydrofuran-2(3H)-one | 250MG | CS-0312594 | 0.97 | 52079-23-9| MFCD00211245 | 102.09
Medchemexpress LLC Protoporphyrin IX (disodium) | 50865-01-5 | 96.5% | 25 MG
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway. It acts as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. This product is promising for research of sonodynamic and photodynamic agents for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Final intermediate in the heme biosynthetic pathway
- Acts as a radiation sensitizer
- Enhances ROS generation and induces DNA damage
- Functions as a photosensitizer
- Undergoes photobleaching by light irradiation
- Accumulates in tumor cells after 5-aminolevulinic acid administration
- Causes selective improvement of basal cell carcinoma
- Promising for research into sonodynamic and photodynamic agents for various cancers
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 500mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Cayman Chemical Mn III ProtoporphyrIn IX Chl
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Medchemexpress LLC Protoporphyrin IX (Standard) | 553-12-8 | 96.1% | 100 MG
Protoporphyrin IX (Standard) is the analytical standard for Protoporphyrin IX. It is intended for research and analytical applications, serving as a final intermediate in the heme biosynthetic pathway. This compound acts as a radiation sensitizer, enhancing ROS generation, and induces DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct light degradation. Protoporphyrin IX is commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard for Protoporphyrin IX
- Acts as a radiation sensitizer and photosensitizer
- Used in HPLC, GC, and MS research experiments
- Suitable for research of sonodynamic and photodynamic agents for various cancers
Apexbio Technology LLC Tin protoporphyrin IX dichloride(Synonyms: Tin Protoporphyrin Dichloride, SnPP, SnPP IX, Tin(IV) Protoporphyrin Dichloride), 10mg, CAS: 14325-05-4.
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Medchemexpress LLC Tetraphenylporphyrin | 917-23-7 | MFCD00011680 | 99.4% | 614.74 g/mol | C44H30N4 | 1 G
Tetraphenylporphyrin is a symmetrically substituted porphyrin-based heterocyclic compound provided as a solid research reagent for synthetic, photophysical, and materials studies.
- High purity solid (99.4%) suitable for analytical and synthetic applications.
- Common building block for supramolecular synthesis and materials research.
- Well-characterized molecular formula C44H30N4 and molecular weight 614.74 g/mol.
- Available in small pack sizes for laboratory-scale work.
- Stable solid form, convenient for storage and handling.
Medchemexpress LLC Cyanocobalamin (Vitamin B12 Standard) | 68-19-9 | 99.95% | 100 MG
Vitamin B12 (Standard) is the analytical standard of Vitamin B12. This product is intended for research and analytical applications. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
- Analytical standard for research and analytical applications
- Supports normal functioning of the brain and nervous system
- Essential for the formation of blood
- Suitable as a reference standard in HPLC, GC, and MS experiments
eMolecules 6305-38-0 | 3-Aminodihydrofuran-2(3H)-one hydrobromide | Oakwood Chemical | MFCD00012723 | 182.017 | C4H8BrNO2 | 99.000 | Br.NC1CCOC1=O | 1g | 537722810
3-Aminodihydrofuran-2(3H)-one hydrobromide | Oakwood Chemical | 6305-38-0 | MFCD00012723 | 182.017 | C4H8BrNO2 | 99.000 | Br.NC1CCOC1=O | 1g | 537722810
Creative Biomart Hemin
The product is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.